Julia Tyler was the first lady of the United States from June 26, 1844, to March 4, 1845, as the second wife of President John Tyler. A member of the influential Gardiner family, she became a prominent socialite early in life who received many notable figures as suitors. She met the recently widowed President Tyler in 1842, and she agreed to marry him after he comforted her in the aftermath of her father's death. They married in secret, and she became first lady immediately upon their marriage, serving in the role for the final eight months of his presidency.

Letitia Tyler was the first lady of the United States from 1841 to 1842 as the first wife of President John Tyler. After meeting in 1808, the two married in 1813. She managed their plantation in Virginia while her husband progressed his political career at the state capital and in Washington, D.C., accompanying him only while he was governor of Virginia. She had a stroke in 1839 that left her permanently disabled.