Julie Alexandra Mayer is a fictional character on the ABC television series Desperate Housewives. The character is played by actress Andrea Bowen, and first appeared in the pilot episode of the series in 2004. She is the daughter of Susan Delfino and Karl Mayer. They share custody of Julie, though she lives primarily with Susan. Julie is characterized as "bright and self-sufficient and extremely mature for her age." She often acts as the parental figure in her relationship with Susan, especially following Susan's divorce from Karl. However, since the 6th season, Julie's personality has changed quite a bit, with her saying she was no longer the "perfect" daughter.

Desperate Housewives is an American comedy-drama mystery television series created by Marc Cherry and produced by ABC Studios and Cherry Productions. It aired for eight seasons on ABC from October 3, 2004, until May 13, 2012, for a total of 180 episodes. Executive producer Marc Cherry served as showrunner. Other executive producers since the fourth season included Bob Daily, George W. Perkins, John Pardee, Joey Murphy, David Grossman, and Larry Shaw.