Juliet Nightingale is a fictional character from the British Channel 4 soap opera Hollyoaks, played by Niamh Blackshaw. Hollyoaks announced the character and Blackshaw's casting on 4 September 2018, with the character making her first appearance as Juliet on 21 November 2018. Juliet was introduced as the half-sister of Romeo Nightingale and the daughter of Donna-Marie Quinn and was brought into the soap as part of the decision to expand their family. Juliet is later revealed to be Mac Nightingale's daughter. The shock twist links her to the established Nightingale family, especially Marnie, who she forms a close bond with. Juliet is initially shown to be an aggressive and harsh character, with an initial storyline seeing her bully Brooke Hathaway due to seeing them as an easy target. However, throughout her tenure, her vulnerable and emotional personality has been explored.

Hollyoaks is a British soap opera which originally began airing on Channel 4 on 23 October 1995. It was created by Phil Redmond, who had previously conceived the soap opera Brookside. From 2005 to 2023, episodes have aired on sister channel E4 a day prior to their broadcast on Channel 4. In 2023, Hollyoaks was removed from Channel 4's early evening schedule, but remains on E4 and Channel 4's on demand service with episodes now uploaded to YouTube.