The Junction Railroad was a railroad created in 1860 to connect lines west of downtown Philadelphia, Pennsylvania, and allow north-south traffic through the metropolitan area for the first time. The railroad consisted of 3.56 miles of double track and 5.3 miles of sidings. It owned no locomotives or rolling stock. The line connected the Philadelphia and Reading Rail Road line at the west end of the Columbia Bridge over the Schuylkill River, crossed the Pennsylvania Railroad line, ran parallel to Market Street, and turned south to connect with the Philadelphia, Wilmington and Baltimore Railroad at Gray's Ferry.

The Reading Company was a Philadelphia-headquartered railroad that provided passenger and freight transport in eastern Pennsylvania and neighboring states from 1924 until its acquisition by Conrail in 1976.