Köln Hauptbahnhof is the central railway station of Cologne, Germany. The station is an important local, national and international transport hub, with many ICE, Eurostar and Intercity trains calling there, as well as regional Regional-Express, RegionalBahn and local S-Bahn trains. EuroNight and Nightjet night services also call at the station. It has frequent connections to Frankfurt by way of the Cologne–Frankfurt high-speed rail line, which starts in southern Cologne. On an average day, about 280,000 travellers frequent the station, making it the fifth busiest station in Germany.

Central stations or central railway stations emerged in the second half of the nineteenth century as railway stations that had initially been built on the edge of city centres were enveloped by urban expansion and became an integral part of the city centres themselves. As a result, "Central Station" is often, but not always, part of the proper name for a railway station that is the central or primary railway hub for a city.