KMOX is a commercial radio station in St. Louis, Missouri. Owned by Audacy, Inc., it is a 50,000 watt Class A clear-channel station with a non-directional signal. The KMOX studios and offices are on Olive Street at Tucker Boulevard in the Park Pacific Building in St. Louis. KMOX refers to itself as "NewsRadio 1120 - The Voice of St. Louis". It is considered the first U.S. station to program all talk shows around the clock.

Talk radio is a radio format containing discussion about topical issues and consisting entirely or almost entirely of original spoken word content rather than outside music. They may feature monologues, dialogues between the hosts, interviews with guests, and/or listener participation which may be live conversations between the host and listeners who "call in" or via voice mail. Listener contributions are usually screened by a show's producers to maximize audience interest and, in the case of commercial talk radio, to attract advertisers.