The Kansas–Nebraska Act of 1854 was a territorial organic act that created the territories of Kansas and Nebraska. It was drafted by Democratic Senator Stephen A. Douglas, passed by the 33rd United States Congress, and signed into law by President Franklin Pierce. Douglas introduced the bill intending to open up new lands to develop and facilitate the construction of a transcontinental railroad. However, the Kansas–Nebraska Act effectively repealed the Missouri Compromise of 1820, stoking national tensions over slavery and contributing to a series of armed conflicts known as "Bleeding Kansas."

Stephen Arnold Douglas was an American politician and lawyer from Illinois. A senator, he was one of two nominees of the badly split Democratic Party for president in the 1860 presidential election, which was won by Republican candidate Abraham Lincoln. Douglas had previously defeated Lincoln in the 1858 United States Senate election in Illinois, known for the pivotal Lincoln–Douglas debates. He was one of the brokers of the Compromise of 1850 which sought to avert a sectional crisis; to further deal with the volatile issue of extending slavery into the territories, Douglas became the foremost advocate of popular sovereignty, which held that each territory should be allowed to determine whether to permit slavery within its borders. This attempt to address the issue was rejected by both pro-slavery and anti-slavery advocates. Douglas was nicknamed the "Little Giant" because he was short in physical stature but a forceful and dominant figure in politics.