Karl Brandt was a German physician and Schutzstaffel (SS) officer in Nazi Germany. Trained in surgery, Brandt joined the Nazi Party in 1932 and became Adolf Hitler's escort doctor in August 1934. A member of Hitler's inner circle at the Berghof, he was selected by Philipp Bouhler, the head of Hitler's Chancellery, to administer the Aktion T4 euthanasia program. Brandt was later appointed the Reich Commissioner of Sanitation and Health. Accused of involvement in human experimentation and other war crimes, Brandt was indicted in late 1946 and faced trial before a U.S. military tribunal along with 22 others in United States of America v. Karl Brandt, et al. He was convicted, sentenced to death, and hanged on 2 June 1948.

Philipp Bouhler was a German senior Nazi Party functionary who was both a Reichsleiter and Chief of the Chancellery of the Führer of the NSDAP. He was also the SS official responsible for the Aktion T4 euthanasia program that killed more than 250,000 disabled adults and children in Nazi Germany, as well as co-initiator of Aktion 14f13, also called Sonderbehandlung, that killed 15,000–20,000 concentration camp prisoners.