The Karuk people are an indigenous people of California, and the Karuk Tribe is one of the largest tribes in California. Karuks are also enrolled in two other federally recognized tribes, the Cher-Ae Heights Indian Community of the Trinidad Rancheria and the Quartz Valley Indian Community.

Indigenous peoples of California, commonly known as Indigenous Californians or Native Californians, are a diverse group of nations and peoples that are indigenous to the geographic area within the current boundaries of California before and after European colonization. There are currently 109 federally recognized tribes in the state and over forty self-identified tribes or tribal bands that have applied for federal recognition. California has the second-largest Native American population in the United States.