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Katalin Karikó
Videos
Katalin "Kati" Karikó is a Hungarian and American biochemist who specializes in ribonucleic acid -mediated mechanisms, particularly in vitro-transcribed messenger RNA for protein replacement therapy.
At the 2023 Nobel Reception in Stockholm
At the 2023 Nobel Reception in Stockholm
Karikó Katalin with a statue of Albert Szent-Györgyi, a fellow Nobel Prize in Physiology or Medicine winner, at the University of Szeged
Karikó Katalin with a statue of Albert Szent-Györgyi, a fellow Nobel Prize in Physiology or Medicine winner, at the University of Szeged
Karikó (right) with Drew Weissman in 2022
Karikó (right) with Drew Weissman in 2022
Katalin Karikó wall painting in Budapest, Hungary
Katalin Karikó wall painting in Budapest, Hungary
COVID-19 vaccine
Videos
A COVID‑19 vaccine is designed to induce immunity against SARS-CoV-2, the virus responsible for coronavirus disease 2019. COVID-19 vaccines help reduce the risk of severe illness, hospitalization and
Katalin Karikó
…RNA. This technology has been licensed by BioNTech and Moderna to develop their protein replacement technologies, but it was also used for their COVID-19 vaccines. The messenger RNA-based technology developed by Karikó and the two most effective vaccines based on it, BioNTech/Pfizer and Moderna, formed the basis…
A conceptual diagram showing three vaccine types for forming SARS‑CoV‑2 proteins to prompt an immune response: (1) RNA vaccine; (2) subunit vaccine; (
A conceptual diagram showing three vaccine types for forming SARS‑CoV‑2 proteins to prompt an immune response: (1) RNA vaccine; (2) subunit vaccine; (3) viral vector vaccine
Vaccine platforms that are being employed for SARS-CoV-2. Whole-virus vaccines include both attenuated and inactivated forms of the virus. Protein and
Vaccine platforms that are being employed for SARS-CoV-2. Whole-virus vaccines include both attenuated and inactivated forms of the virus. Protein and peptide subunit vaccines are usually combined with an adjuvant to enhance immunogenicity. The main emphasis in SARS-CoV-2 vaccine development has been on using the whole spike protein in its trimeric form, or its components, such as the RBD region. Multiple non-replicating viral vector vaccines have been developed, particularly focused on
Diagram of the operation of an RNA vaccine. Messenger RNA contained in the vaccine enters cells and is translated into viral proteins, which trigger a
Diagram of the operation of an RNA vaccine. Messenger RNA contained in the vaccine enters cells and is translated into viral proteins, which trigger an immune response.
Vial of Novavax vaccine from clinical trials at Thackray Museum of Medicine
Vial of Novavax vaccine from clinical trials at Thackray Museum of Medicine