Kathleen Sebelius is an American politician who served as the 21st United States Secretary of Health and Human Services from 2009 until 2014. As Secretary of Health and Human Services, Sebelius was instrumental in overseeing the implementation of the Affordable Care Act. Before becoming secretary, she served as the 44th governor of Kansas from 2003 to 2009, the second woman to hold that office. She is a member of the Democratic Party. Sebelius was the Democratic respondent to the 2008 State of the Union address and is chair-emerita of the Democratic Governors Association. She is CEO of Sebelius Resources LLC.

The United States secretary of health and human services is the head of the United States Department of Health and Human Services, and serves as the principal advisor to the president of the United States on all health matters. The secretary is a member of the United States Cabinet. The office was formerly Secretary of Health, Education, and Welfare. In 1980, the Department of Health, Education, and Welfare was renamed the Department of Health and Human Services, and its education functions and Rehabilitation Services Administration were transferred to the new United States Department of Education. Patricia Roberts Harris headed the department before and after it was renamed.