Kalanikauikaʻalaneo Kai Keōpūolani-Ahu-i-Kekai-Makuahine-a-Kama-Kalani-Kau-i-Kealaneo (1778–1823) was a queen consort of Hawaiʻi and the highest ranking wife of King Kamehameha I.

Kamehameha II was the second king of the Kingdom of Hawaii from 1819 to 1824. His birth name was Liholiho and full name was Kalaninui kua Liholiho i ke kapu ʻIolani. It was lengthened to Kalani Kaleiʻaimoku o Kaiwikapu o Laʻamea i Kauikawekiu Ahilapalapa Kealiʻi Kauinamoku o Kahekili Kalaninui i Mamao ʻIolani i Ka Liholiho when he took the throne.