Keetmanshoop is a town in the ǁKaras Region of southern Namibia, lying on the Trans-Namib Railway from Windhoek to Upington in South Africa. It is named after Johann Keetman, a German industrialist and benefactor of the city.

The ǁKharas Region is the southernmost, largest, and least densely populated of the 14 regions of Namibia; its capital is Keetmanshoop. The name assigned to the region reflects the prominence of the Karas mountain range in its southern part. The ǁKharas region contains the municipality of Keetmanshoop, the towns Karasburg, Lüderitz and Oranjemund, and the self-governed villages Aroab, Berseba, Bethanie, Koës and Tses.