Kenedy is a city in Karnes County, Texas, United States, named for Mifflin Kenedy, who bought 400,000 acres (1,600 km2) and wanted to develop a new town that would carry his name. The population was 3,473 at the 2020 census, up from 3,296 at the 2010 census.

Karnes County is a county in the U.S. state of Texas. As of the 2020 census, the population was 14,710. Its county seat is Karnes City. The county is named for Henry Karnes, a soldier in the Texas Revolution. The former San Antonio and Aransas Pass Railway passed through Karnes County in its connection linking San Antonio with Corpus Christi.