Kenova is a city in Wayne County, West Virginia, United States, situated at the confluence of the Ohio and Big Sandy rivers. The city's name is a portmanteau of Kentucky, Ohio, and Virginia (Va), owing to its location where the three states met before the creation of West Virginia. The population was 3,030 at the 2020 census. It is part of the Huntington–Ashland metropolitan area.

Wayne County is the westernmost county in the U.S. state of West Virginia. As of the 2020 census, the population was 38,982. Its county seat is Wayne. The county was founded in 1842 and named for General "Mad" Anthony Wayne. Wayne County is part of the Huntington–Ashland, WV–KY–OH Metropolitan Statistical Area.