Khanty-Mansiysk is a city in west-central Russia. Technically, it is situated on the eastern bank of the Irtysh River, 15 kilometers (9.3 mi) from its confluence with the Ob, in the oil-rich region of Western Siberia. Though it is an independent city, Khanty-Mansiysk also functions as the administrative centre of Khanty-Mansiysky District, and the administrative center of Khanty-Mansi Autonomous Okrug–Yugra.

The Irtysh is a river in Russia, China, and Kazakhstan. It is the chief tributary of the Ob and is also the longest tributary river in the world.