Khizr Khan was the founder of the Sayyid dynasty, the fourth ruling dynasty of the Delhi sultanate, in northern India soon after the invasion of Timur and the fall of the Tughlaq dynasty. Khizr Khan was Governor of Multan under the Tughlaq ruler, Firuz Shah Tughlaq, and was known to be an able administrator. He did not take up any royal title due to fear of invasion by Amir Timur and contended himself with the titles of Rayat-i-Ala and Masnad-i-Aali or. During his reign, coins were continued to be struck in the name of previous Tughlaq rulers. After his death on 20 May 1421, he was succeeded by his son Mubarak Khan, who took the title of Muizz-ud-Din Mubarak Shah.

The Sayyid dynasty was the fourth dynasty of the Delhi Sultanate, with four rulers ruling from 1414 to 1451 for 37 years. The first ruler of the dynasty, Khizr Khan, who was the Timurid vassal of Multan, conquered Delhi in 1414, while the rulers proclaimed themselves the Sultans of the Delhi Sultanate under Mubarak Shah, which succeeded the Tughlaq dynasty and ruled the Sultanate until they were displaced by the Lodi dynasty in 1451.