Khosrow and Shirin is the title of a famous tragic romance by the Persian poet Nizami Ganjavi (1141–1209), who also wrote Layla and Majnun. It tells a highly elaborated fictional version of the story of the love of the Sasanian king Khosrow II for the Christian Shirin, who becomes queen of Persia. The essential narrative is a love story of Persian origin which was already well known from the great epico-historical poem the Shahnameh and other Persian writers and popular tales, and other works have the same title.

Nizami Ganjavi, Nizami Ganje'i, Nizami, or Nezāmi, whose formal name was Jamal ad-Dīn Abū Muḥammad Ilyās ibn-Yūsuf ibn-Zakkī, was a 12th-century Muslim poet. Nizami is considered the greatest romantic epic poet in Persian literature, who brought a colloquial and realistic style to the Persian epic. His heritage is widely appreciated in Afghanistan, Republic of Azerbaijan, Iran, the Kurdistan region and Tajikistan.