King Edward VI Handsworth Grammar School for Boys, formerly and commonly Handsworth Grammar School, is a grammar school that admits boys from the age of eleven. The school was founded in 1862 and is located in Handsworth, Birmingham, England. it is situated just off the A41, near the junction with the A4040. King Edward Handsworth Grammar School is sometimes abbreviated as HGS. The headmaster is Simon N Bird.

Handsworth is an inner-city area of Birmingham in the West Midlands, England. Historically in Staffordshire, Handsworth lies just outside Birmingham City Centre and near the town of Smethwick.