The Kingdom of the Two Sicilies was a kingdom in Southern Italy from 1816 to 1861 under the control of a cadet branch of the Spanish Bourbons. The kingdom was the largest sovereign state by population and size in Italy before Italian unification, comprising Sicily and most of the area of today's Mezzogiorno in covering all of the Italian Peninsula south of the Papal States.

Southern Italy, also known as Meridione or Mezzogiorno, is a macroregion of Italy consisting of its southern regions.