Kisatchie National Forest, the only National forest in Louisiana, United States, is located in the forested piney hills and hardwood bottoms of seven central and northern parishes. It is part of the Cenozoic uplands and has large areas of longleaf pine forests. It is one of the largest pieces of natural landscape in Louisiana, with some 604,000 acres (2,440 km2) of public land, more than half of which is vital longleaf pine and flatwoods vegetation. These support many rare plant and animal species. There are also rare habitats, such as hillside seepage bogs and calcareous prairies. The forest also contains and provides a buffer for the Kisatchie Hills Wilderness, a nationally designated wilderness area that contributes to protecting biodiversity of the coastal plain region of the United States.

The Louisiana pine snake is a species of large, non-venomous, constrictor in the family Colubridae. This powerful snake is notable because of its large eggs and small clutch sizes. The Louisiana pine snake is indigenous to west-central Louisiana and East Texas, where it relies strongly on Baird's pocket gophers for its burrow system and as a food source. The Louisiana pine snake is rarely seen in the wild, and is considered to be one of the rarest snakes in North America. The demise of the species is due to its low fecundity coupled with the extensive loss of suitable habitat - the longleaf pine savannas in the Gulf coastal plain of the southeastern United States. Management activities are being conducted to promote the species' recovery.