Kiss of the Spider Woman is a 1976 novel by Argentine writer Manuel Puig. It depicts the daily conversations between two cellmates in an Argentine prison, Molina and Valentín, and the intimate bond they form in the process. It is generally considered Puig's most successful work.

Juan Manuel Puig Delledonne, commonly called Manuel Puig, was an Argentine author. Among his best-known novels are La traición de Rita Hayworth, Boquitas pintadas, and El beso de la mujer araña which was adapted into the film released in 1985, directed by the Argentine-Brazilian director Héctor Babenco; and a Broadway musical in 1993.