The Kozloduy Nuclear Power Plant is a nuclear power plant in Bulgaria situated 180 kilometres (110 mi) north of Sofia and 5 kilometres (3.1 mi) east of Kozloduy, a town on the Danube river, near the border with Romania. It is the country's only nuclear power plant and the largest in the region. The construction of the first reactor began on 6 April 1970.

Kozloduy is a town in northwest Bulgaria, located in Vratsa Province, on the Danube River. The city was liberated from Ottoman rule on 23 November 1877 by the Romanian Army under the command of the Imperial Russian Army. Kozloduy is best known for the Kozloduy Nuclear Power Plant, Bulgaria's only nuclear power plant, which is located nearby, as well as the second-largest Bulgarian Danubian island, Kozloduy Island. The city is also known for the ship Radetzky, the boat in which the poet and revolutionary Hristo Botev and with 200 others crossed the Danube River in a final attempt to gather an army and liberate Bulgaria from the Ottoman Empire.