Qyzylorda Region is a region of Kazakhstan. Its capital is the city of Qyzylorda, with a population of 234 736. The region itself has a population of 823 251. Other notable settlements include Aral, Kazaly (Kazalinsk) and the Russian-administered Baikonur, which services the Baikonur Cosmodrome. The total area of the province is 226,000 square kilometers (87,000 sq mi).

Kazakhstan is divided into 17 regions. The regions are further subdivided into districts. Three cities, Almaty, Shymkent, and the capital city Astana, do not belong to their surrounding regions.