L.A. by Night is an American actual play web series where the cast plays as vampires using the fifth edition Vampire: The Masquerade ruleset. It is set canonically in the World of Darkness series after the events of Vampire: The Masquerade – Bloodlines and focuses on Kindred society in Los Angeles. It premiered in September 2018; the show's current storyline concluded with its fifth season in 2021. A sequel series, titled NY by Night, started in July 2022.

Vampire: The Masquerade is a tabletop role-playing game created by Mark Rein-Hagen and released in 1991 by White Wolf Publishing as the first of several Storyteller System games for its World of Darkness setting line. It is set in a fictionalized "gothic-punk" version of the modern world where players assume the role of vampires, who are referred to as "Kindred." and deal with their night-to-night struggles against their own bestial natures, vampire hunters, and each other.