LATAM Cargo Chile is a cargo airline based in Santiago, Chile and the freight subsidiary of the LATAM Airlines Group. It is operating cargo flights within South America, to Europe and North America from its hubs at Miami International Airport and Arturo Merino Benítez International Airport.

Cargo airlines are airlines mainly dedicated to the transport of cargo by air. Some cargo airlines are divisions or subsidiaries of larger passenger airlines. In 2018, airline cargo traffic represented 262,333 million tonne-kilometres with a 49.3% load factor: 52.1% for dedicated cargo operations, and 47.9% within mixed operations.