Lactuca, commonly known as lettuce, is a genus of flowering plants in the family Asteraceae. The genus includes at least 50 species, distributed worldwide, but mainly in temperate Eurasia.

Lettuce is an annual plant of the family Asteraceae. It is most often grown as a leaf vegetable, but sometimes for its stem and seeds. Lettuce is most often used for salads, although it is also seen in other kinds of food, such as soups, sandwiches and wraps; it can also be grilled. One variety, celtuce, is grown for its stems, which are eaten either raw or cooked. In addition to its main use as a leafy green, it has also gathered religious and medicinal significance over centuries of human consumption. Europe and North America originally dominated the market for lettuce, but by the late 20th century the consumption of lettuce had spread throughout the world. As of 2021, world production of lettuce and chicory was 27 million tonnes, 53 percent of which came from China.