Lafayette County is a county located in the U.S. state of Arkansas. As of the 2020 census, the population was 6,308, making it the third-least populous county in Arkansas. The county seat is Lewisville. Lafayette County was formed on October 15, 1827, and named in honor of the Marquis de Lafayette, a French military hero of the American Revolutionary War. It is a dry county; therefore, the sale of alcohol is prohibited.

Lewisville is a city in Lafayette County, Arkansas, United States. The population was 1,280 at the 2010 census. It is the county seat of Lafayette County.