The Lafayette-West Lafayette, Indiana Metropolitan Statistical Area, as defined by the United States Census Bureau, is an area consisting of three counties in Indiana, anchored by the cities of Lafayette and West Lafayette. As of the July 1, 2021, the MSA had an estimated population of 224,709. Metro area population in 2021 is 237,130 and was 235,066 in 2020, a growth of 16% over 2010. In 2010, the Lafayette, Indiana, metro area population was 210,297.

Lafayette is a city in and is the county seat of Tippecanoe County, Indiana, United States, located 63 miles (101 km) northwest of Indianapolis and 125 miles (201 km) southeast of Chicago. According to the 2020 census, the population of Lafayette was 70,783. West Lafayette, on the other side of the Wabash River, is home to Purdue University, which contributes significantly to both communities. Together, they form the core of the Lafayette metropolitan area, which had a population of 235,066 in 2020.