Laguna's 2nd congressional district is one of the seven congressional districts of the Philippines in the province of Laguna, formerly La Laguna. It has been represented in the House of Representatives of the Philippines since 1916 and earlier in the Philippine Assembly from 1907 to 1916. The district consists of the city of Cabuyao and adjacent municipalities of Bay and Los Baños. It is currently represented in the 19th Congress by Ruth Mariano-Hernandez of the Lakas–CMD.

Cabuyao, officially the City of Cabuyao, is a 1st class component city in the province of Laguna, Philippines. According to the 2020 census, it has a population of 355,330 people.