Lai Chi Kok Road is a road in western Kowloon, Hong Kong. It links Lai Chi Kok to Mong Kok, via Tai Kok Tsui, Sham Shui Po and Cheung Sha Wan. It starts from a junction with Nathan Road near Pioneer Centre in the south and ends near Mei Foo Sun Chuen. The road is bidirectional except the section at Lai Chi Kok, between the junction with Butterfly Valley Road and Mei Foo Sun Chuen, where it serves New Territories-bound traffic only. The Kowloon-bound traffic uses Cheung Sha Wan Road, separated by the flyover of Kwai Chung Road. The road once hosted shipyards, fish, meat and vegetable wholesale markets, which were moved closer to the coast after extensive reclamation.

Lai Chi Kok is a neighbourhood in Kowloon, Hong Kong, east of Kwai Chung and west of Cheung Sha Wan. Mei Foo Sun Chuen is the largest housing estate in the area and also the largest in Hong Kong with 99 blocks. Administratively, it belongs to Sham Shui Po District.