Lake Nona Medical City is a 650-acre (260 ha) health and life sciences park in Orlando, Florida, United States. It is located near Orlando International Airport and within the master-planned community of Lake Nona. The city is home to the University of Central Florida's Health Sciences Campus, which includes the university's College of Medicine and Burnett School of Biomedical Sciences. In the future, the campus will also house UCF's University of Central Florida College of Nursing, the University of Central Florida College of Dental Medicine, and a teaching hospital.

The University of Central Florida (UCF) is a public research university with its main campus in unincorporated Orange County, Florida. It is part of the State University System of Florida. With 68,442 students as of the fall 2022 semester, UCF has the fourth-largest on-campus student body of any public university in the United States. UCF is classified among "R1: Doctoral Universities – Very high research activity" and is accredited by the Commission on Colleges of the Southern Association of Colleges and Schools.