The Lancaster pistol was a multi-barrelled handgun produced in England in the mid to late 19th century, chambered in a variety of centrefire pistol calibres—chiefly .38 S&W, .450 Adams, .455 Webley, and .577 inch. The designer, London gunsmith Charles Lancaster, began his career in 1847 as an apprentice to his father, Charles Sr. During the 1850s he invented oval bore rifling and the gas check bullet.

The pepper-box revolver or simply pepperbox is a multiple-barrel firearm, mostly in the form of a handgun, that has three or more gun barrels in a revolving mechanism. Each barrel holds a single shot, and the shooter can manually rotate the whole barrel assembly to sequentially index each barrel into alignment with the lock or hammer, similar to rotation of a revolver's cylinder.