United States Anti-Doping Agency v. Lance Armstrong, the Lance Armstrong doping case, was a major doping investigation that led to retired American road racing cyclist Lance Armstrong being stripped of his seven consecutive Tour de France titles, along with one Olympic medal, and his eventual admission to using performance-enhancing drugs. The United States Anti-Doping Agency (USADA) portrayed Armstrong as the ringleader of what it called "the most sophisticated, professionalized and successful doping program that sport has ever seen."

Lance Edward Armstrong is an American former professional road racing cyclist. He achieved international fame for winning the Tour de France a record seven consecutive times from 1999 to 2005, but was stripped of his titles after an investigation into doping allegations, called the Lance Armstrong doping case, found he used performance-enhancing drugs over his career. He is currently banned for life from all sanctioned bicycling events.