Laredo is a city in the U.S. state of Texas and seat of Webb County, on the north bank of the Rio Grande in South Texas, across from Nuevo Laredo, Tamaulipas, Mexico. Founded in 1755, Laredo grew from a village to the capital of the short-lived Republic of the Rio Grande to the largest inland port on the Mexican border. Laredo's economy is primarily based on international trade with Mexico, and as a major hub for three areas of transportation: land, rail, and air cargo. The city is on the southern end of I-35, which connects manufacturers in northern Mexico through Interstate 35 as a major route for trade throughout the U.S. It has four international bridges and one railway bridge.

Webb County is a county located in the U.S. state of Texas. As of the 2020 census, its population was 267,114. Its county seat is Laredo. The county was named after James Webb (1792–1856), who served as secretary of the treasury, secretary of state, and attorney general of the Republic of Texas, and later judge of the United States District Court following the admission of Texas to statehood. By area, Webb County is the largest county in South Texas and the sixth-largest in the state. Webb County comprises the Laredo metropolitan area. Webb County is the only county in the United States to border three foreign states or provinces, sharing borders with Coahuila, Nuevo Leon, and Tamaulipas.