Last Life in the Universe is a 2003 Thai romantic crime film directed by Pen-Ek Ratanaruang. The film is notable for being trilingual; the two main characters flit from Thai to Japanese to English as their vocabulary requires. The film stars Japanese actor Tadanobu Asano and Sinitta Boonyasak.

Pen-ek Ratanaruang is a Thai film director and screenwriter. He is best known for his arthouse work, Last Life in the Universe, and is considered to be one of Thai cinema's leading "new wave" auteurs, alongside Wisit Sasanatieng and Apichatpong Weerasethakul. He goes by the nickname Tom and is sometimes credited as Tom Pannet.