Leatherwood Plantation of 10,000 acres was located in Henry County, Virginia, where American Founding Father Patrick Henry lived from 1779 until 1784. The plantation is probably named after Leatherwood Creek, a tributary to the Smith River (Virginia), which ran through the property.

Henry County is a county located in the U.S. state of Virginia. As of the 2020 census, the population was 50,948. The county seat is usually identified as Martinsville; however, the administration building, county courthouse, and Henry County Sheriff's Office are located on Kings Mountain Road in Collinsville.The Henry County Adult Detention Center is located on DuPont Road in Martinsville.