Lee County is a county located in the U.S. state of North Carolina. As of the 2020 census, the population was 63,285. The county seat is Sanford.

Sanford is a city in Lee County, North Carolina, United States. The population was 30,261 at the 2020 census. It is the county seat of Lee County. The geographic center of North Carolina is located northwest of the city, in Chatham County.