Lee Mi-sook is a South Korean actress. One of the best-known actresses of 1980s Korean cinema, Lee's most famous films from this era include Bae Chang-ho's Whale Hunting and The Winter That Year Was Warm, Lee Doo-yong's Mulberry and Eunuch, and Kwak Ji-kyoon's Wanderer in Winter. She retired from film after getting married in 1987, though she still appeared on television in dramas such as How's Your Husband? (1993). Then a decade later, Lee made her comeback with an award-winning leading role in E J-yong's feature debut An Affair (1998). She has since remained active in film and television, notably in the May–December romance Solitude (2002), the Dangerous Liaisons adaptation Untold Scandal (2003), the mockumentary Actresses (2009), the family dramas Smile, Mom (2010), and Queen of Tears (2024).

The Empire is a South Korean television series starring Kim Sun-a, Ahn Jae-wook, and Lee Mi-sook. It premiered on JTBC on September 24, 2022, and aired every Saturday and Sunday at 22:30 (KST). It is also available for streaming on Viu in selected regions.