Les Misérables in Concert: The 25th Anniversary was performed and filmed at The O2 Arena in North Greenwich, London, England, on 3 October 2010 at 1:30 pm and 7:00 pm. It marked the 25th anniversary of the original West End production of Les Misérables, which was based on Victor Hugo's 1862 novel, and has been running since October 1985.

Les Misérables is a French historical novel by Victor Hugo, first published in 1862, that is considered one of the greatest novels of the 19th century. Les Misérables has been popularized through numerous adaptations for film, television and the stage, including a musical.