Lewis Thornton Powell was an American Confederate soldier who attempted to assassinate William Henry Seward as part of the Lincoln assassination plot. Wounded at the Battle of Gettysburg, he later served in Mosby's Rangers before working with the Confederate Secret Service in Maryland. John Wilkes Booth recruited him into a plot to kidnap Lincoln and turn the president over to the Confederacy, but then decided to assassinate Lincoln, Seward, and Vice President Andrew Johnson instead, and assigned Powell the task to kill Seward.

George Andrew Atzerodt was a German American repairman, Confederate sympathizer, and conspirator in the assassination of U.S. President Abraham Lincoln. He was assigned to assassinate Vice President Andrew Johnson, but lost his nerve and made no attempt. Atzerodt was tried by a military tribunal, sentenced to death for conspiracy, and hanged along with three other conspirators.