Lick Run is a tributary of Little Fishing Creek in Lycoming County and Columbia County, in Pennsylvania, in the United States. It is approximately 5.2 miles (8.4 km) long and flows through Jordan Township in Lycoming County and Pine Township, in Columbia County. The watershed of the stream has an area of 4.40 square miles (11.4 km2). The entire drainage basin is considered to be a Coldwater Fishery and a portion of the stream is considered to be Class A Wild Trout Waters. At least one bridge crosses the stream.

Little Fishing Creek is a tributary of Fishing Creek in Sullivan County, Lycoming County, and Columbia County, in Pennsylvania, in the United States. It is approximately 23.5 miles (37.8 km) long and flows through eight townships. The watershed of the creek has an area of 68.1 square miles (176 km2). The creek has six named tributaries, of which the largest are Spruce Run and West Branch Run.