Like a Velvet Glove Cast in Iron is a graphic novel by American cartoonist Daniel Clowes. The book follows a fantastic and paranoid plot, differing in tone from the stark realism of Clowes' later more widely known Ghost World. It contains nightmarish imagery, including dismemberment, deformed people and animals, and sexual fetishism.

Daniel Gillespie Clowes is an American cartoonist, graphic novelist, illustrator, and screenwriter. Most of Clowes's work first appeared in Eightball, a solo anthology comic book series. An Eightball issue typically contained several short pieces and a chapter of a longer narrative that was later collected and published as a graphic novel, such as Like a Velvet Glove Cast in Iron (1993), Ghost World (1997), David Boring (2000) and Patience (2016). Clowes's illustrations have appeared in The New Yorker, Newsweek, Vogue, The Village Voice, and elsewhere. With filmmaker Terry Zwigoff, Clowes adapted Ghost World into a 2001 film and another Eightball story into the 2006 film, Art School Confidential. Clowes's comics, graphic novels, and films have received numerous awards, including a Pen Award for Outstanding Work in Graphic Literature, over a dozen Harvey and Eisner Awards, and an Academy Award nomination.