Lili Elbe is an opera in two acts composed by Tobias Picker, with a libretto by Aryeh Lev Stollman, starring Lucia Lucas as Lili Elbe. Based on the life of Lili Elbe and the book Man into Woman: An Authentic Record of a Change of Sex, the opera premiered on 22 October 2023, and received "Best World Premiere" in the 2023 Oper! Awards.

Tobias Picker is an American composer, pianist, and conductor, noted for his orchestral works Old and Lost Rivers, Keys To The City, and The Encantadas, as well as his operas Emmeline, Fantastic Mr. Fox, An American Tragedy and Lili Elbe, among many other works.