In gridiron football, a lineman is a player who specializes in play at the line of scrimmage. The linemen of the team currently in possession of the ball are the offensive line, while linemen on the opposing team are the defensive line. A number of NFL rules specifically address restrictions and requirements for the offensive line, whose job is to help protect the quarterback from getting sacked for a loss, or worse, fumbling. The defensive line is covered by the same rules that apply to all defensive players. Linemen are usually the largest players on the field in both height and weight, since their positions usually require less running and more strength than skill positions.

Center or centre (C) is a position in American football. The center is the innermost lineman of the offensive line on a football team's offense. The center is also the player who passes the ball between his legs to the quarterback at the start of each play.