Lise Meitner was an Austrian-Swedish physicist who was one of those responsible for the discovery of the element protactinium and nuclear fission. While working on radioactivity at the Kaiser Wilhelm Institute of Chemistry in Berlin, she discovered the radioactive isotope protactinium-231 in 1917. In 1938, Meitner and her nephew, the physicist Otto Robert Frisch, discovered nuclear fission. She was praised by Albert Einstein as the "German Marie Curie".

Protactinium is a chemical element; it has symbol Pa and atomic number 91. It is a dense, radioactive, silvery-gray actinide metal which readily reacts with oxygen, water vapor, and inorganic acids. It forms various chemical compounds, in which protactinium is usually present in the oxidation state +5, but it can also assume +4 and even +3 or +2 states. Concentrations of protactinium in the Earth's crust are typically a few parts per trillion, but may reach up to a few parts per million in some uraninite ore deposits. Because of its scarcity, high radioactivity, and high toxicity, there are currently no uses for protactinium outside scientific research, and for this purpose, protactinium is mostly extracted from spent nuclear fuel.