Birkenhead is a town in Wirral, Merseyside, England. Its central area contains 150 buildings that are recorded in the National Heritage List for England as designated listed buildings. Of these, six are listed at Grade I, the highest of the three grades, six at Grade II*, the middle grade, and the others are at Grade II, the lowest grade. This list contains the listed buildings in the central area of the town, and the other listed buildings are to be found in separate lists.

Birkenhead Priory is in Priory Street, Birkenhead, Merseyside, England. It is the oldest standing building on Merseyside. The site comprises the medieval remains of the priory itself, the priory chapter house, and the remains of St Marys church. All three are recorded in the National Heritage List for England, though at different grades.