The Little Creek-Cape Charles Ferry was a passenger ferry service operating across the mouth of the Chesapeake Bay from the 1930s until 1964. Known also as the Princess Anne-Kiptopeke Beach Ferry or Little Creek-Kiptopeke Beach Ferry, the service connected Virginia Beach, Virginia with Cape Charles on the Eastern Shore of Virginia. Departures from and arrivals to Cape Charles were matched with times of Pennsylvania Railroad passenger trains such as the Del-Mar-Va Express and the Cavalier that operated the length of the Delmarva Peninsula.

SS Princess Anne was a Virginia Ferry Company (VFC) steamship that plied the route across Chesapeake Bay between Little Creek, near Norfolk, and Kiptopeke Beach, at the southern end of the Eastern Shore of Virginia. She was known for her streamlined superstructure, designed by Raymond Loewy, which attracted the attention of the newsreels and the nautical press.