On 14 October 2022, the British tabloid newspaper the Daily Star began a livestream of an iceberg lettuce next to a framed photograph of Liz Truss, who had recently been appointed the prime minister of the United Kingdom. This act followed an opinion piece in The Economist that compared the expected brevity of Truss's premiership to the shelf life of a head of lettuce, with the October 2022 United Kingdom government crisis occurring weeks into her tenure and leading many political commentators to opine that Truss's resignation was imminent. She announced her resignation as prime minister on 20 October 2022, before the lettuce had wilted; the Daily Star subsequently declared the lettuce "victorious" over Truss.

Liz Truss's tenure as Prime Minister of the United Kingdom began on 6 September 2022 when she accepted an invitation from Elizabeth II to form a government, succeeding Boris Johnson, and ended 49 days later on 25 October upon her resignation. As prime minister, she served simultaneously as First Lord of the Treasury, Minister for the Civil Service, and Minister for the Union.