Locus coeruleus
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The locus coeruleus, also spelled locus caeruleus or locus ceruleus, is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic. It is a part of the reticular
Micrograph showing the locus coeruleus (upper-right of image) in an axial section of the pons. The fourth ventricle (quasi-triangular white area) is in the upper-left of the image. The midline is seen on the left. The large white area in the upper-left corner is where the cerebellum would be. HE-LFB stain.
Locus coeruleus highlighted in green.
Micrograph showing the locus coeruleus. HE-LFB stain
The hypothalamic–pituitary–adrenal axis is a neuroendocrine axis that controls the secretion of corticosteroid stress hormones. The HPA axis has three components: the hypothalamus, the pituitary gland
Schematic overview of the hypothalamic-pituitary-adrenal (HPA) axis. Stress activates the HPA-axis and thereby enhances the secretion of glucocorticoids from the adrenals.
